Complete Concept Guide (100% Curriculum Coverage)
1. Mendel's Monohybrid Cross ($3 : 1$)
Mendel crossed pure tall ($TT$) and pure dwarf ($tt$) pea plants. In the $F_1$ generation, all offspring were Tall ($Tt$) because the tall trait is Dominant. Self-pollinating $F_1$ yielded the $F_2$ generation with:
• Phenotypic Ratio: $\mathbf{3\text{ Tall} : 1\text{ Dwarf}}$
• Genotypic Ratio: $\mathbf{1\text{ TT} : 2\text{ Tt} : 1\text{ tt}}$
2. Dihybrid Cross ($9 : 3 : 3 : 1$)
Crossing round-yellow seeds ($RRYY$) with wrinkled-green seeds ($rryy$) produced a novel mix in $F_2$: Round-Yellow (9), Round-Green (3), Wrinkled-Yellow (3), Wrinkled-Green (1), proving the Law of Independent Assortment!
3. Genetic Sex Determination in Humans
Human somatic cells have 23 pairs of chromosomes: 22 pairs of autosomes and 1 pair of sex chromosomes. Females have identical XX chromosomes; males have XY chromosomes.
• If an egg ($X$) is fertilized by an $X$-bearing sperm → Baby Girl (XX).
• If an egg ($X$) is fertilized by a $Y$-bearing sperm → Baby Boy (XY).
Scientific Truth: Genetic sex is determined strictly by the father's sperm, never by the mother!
Check Your Understanding (Diagnostic Practice Questions)
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1
Why did Gregor Mendel choose the garden pea plant (Pisum sativum) for his genetic experiments?
Reveal Answer & Explanation
Answer: Pea plants have clear distinct contrasting traits, short lifespans, produce large numbers of seeds, and can easily be cross-pollinated or self-pollinated.
Distinct contrasting traits and short life.
2
A cross between a tall pea plant (TT) and a short pea plant (tt) resulted in progeny that were all tall. Why?
Reveal Answer & Explanation
Answer: Because the allele for tallness ($T$) is dominant over the allele for shortness ($t$); in the heterozygous $Tt$ state, only the dominant trait expresses.
Tallness is the dominant trait.
3
Explain how the sex of a child is determined genetically in human beings.
Reveal Answer & Explanation
Answer: Females produce eggs carrying only X chromosomes. Males produce sperm carrying either an X or a Y chromosome. Fertilization by an X-sperm produces a girl (XX); fertilization by a Y-sperm produces a boy (XY).
Determined by X or Y sperm from father.
4
What is the genotypic ratio of a monohybrid cross in the $F_2$ generation?
Reveal Answer & Explanation
Answer: $1 : 2 : 1$ ($1\text{ TT} : 2\text{ Tt} : 1\text{ tt}$).
1:2:1.
5
Can an acquired trait (such as weight loss due to starvation) be inherited by offspring? Explain.
Reveal Answer & Explanation
Answer: No, acquired traits do not alter the DNA sequences in reproductive germ cells (gametes); only genetic alterations in germ cells can be passed to future generations.
Does not alter germ cell DNA.
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